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gerBC [Wed Jan 06 2016 13:28:50 GMT+0100 (CET)]
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gerBC [Wed Jan 06 2016 13:28:50 GMT+0100 (CET)]

lipoprotein, nutrient receptor, germination response to the combination of glucose, fructose, and KCl
locus
BSU35820
pI
9.00
mw
42.00 kDa
function
germination
product
nutrient receptor
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.1|Germinant receptors]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|germination], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigG regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,691,372 -> 3,692,496

    The protein

    Protein family

  • gerABKC lipoprotein family (according to Swiss-Prot)
  • [SW|Domains]

  • has an N-terminal signal sequence, lipidated on a Cys residue adjacent to the signal peptide [Pubmed|23335419]
  • Structure

  • [PDB|3N54] [Pubmed|20654628]
  • [SW|Localization]

  • outer surface of the inner spore membrane [Pubmed|23335419,21685283]
  • [SW|Interactions]

  • [SW|GerBA]-[SW|GerBB]-[SW|GerBC] (tentative receptor complex) [Pubmed|21696470]
  • [SW|GerBC] is part of the [SW|germinosome] in the spore inner membrane [Pubmed|21696470]
  • Additional information

  • 700 molecules are present per spore [Pubmed|23749970]
  • Expression and Regulation

    Operon

  • ''[SW|gerBA]-[SW|gerBB]-[SW|gerBC]'' [Pubmed|8012571]
  • [SW|Sigma factor]

  • [protein|search|SigG] [Pubmed|15699190,8012571]
  • Regulation

  • expressed late during sporulation in the forespore ([protein|search|SigG]) [Pubmed|15699190,8012571]
  • Additional information

  • 700 molecules are present per spore [PubMed|23749970]
  • References

  • 23396907,16740944,23749970,24752279,7812448,12670969,15774895,15699190,8012571,16352818,20654628,21685283,21696470,22493018,23335419