putative CDP-glycerol:glycerol phosphate glycerophosphotransferase
function
biosynthesis of teichoic acid
product
putative CDP-glycerol:glycerol
phosphate glycerophosphotransferase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|essential genes], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|PhoP regulon], [SW|WalR regulon]Gene
Coordinates on the chromosome (coding sequence)
3,682,173 -> 3,683,318
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Catalyzed reaction/ biological activity
adds a single glycerol phosphate residue to the non-reducing end of the undecaprenol-phosphate-linked N-acetylmannosamine-β(1,4)-N-acetylglucosamine-1-phosphate [Pubmed|17660278]Protein family
CDP-glycerol glycerophosphotransferase family (according to Swiss-Prot)[SW|Localization]
cell membrane [Pubmed|17660278]Expression and Regulation
Operon
''[protein|search|tagA]-[protein|search|tagB]'' [Pubmed|7952180][SW|Sigma factor]
[protein|search|SigA] [Pubmed|7581998]Regulation
repressed when phosphate is available ([protein|search|PhoP]) [Pubmed|9457886]Regulatory mechanism
[protein|search|PhoP]: transcription repression [Pubmed|9457886][protein|search|WalR]: transcription activation [Pubmed|12950927]References
Reviews
Original publications
18156271,9457886,17660278,7581998,16150696,7952180,12950927,15547257 
