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yvbW [2018-05-30 17:49:20]
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yvbW [2018-05-30 17:49:20]

putative leucine permease
locus
BSU34010
pI
9.84
mw
49.01 kDa
protein length
447 aa Sequence Blast
gene length
1341 bp Sequence Blast
function
unknown
product
putative leucine permease
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,489,910 → 3,491,253

    The protein

    Paralogous protein(s)

  • [protein|9AD0E43119BDC65D5F67CE55CD9417E1E6BAE058|YbxG], [protein|9BFB16C12B31ABD70BBB921BCB9E4201E3BDC92D|RocC], [protein|B46A8BCEC56E6252712E30F8BF8DA6B836FDE2F6|RocE], [protein|B6A920650919D5BBBD75CCA58C30A0D8ECE64DA3|YbgF], [protein|C7FEA1D9C7C96C39CEE83CE3F13D412DE6AFE10E|YdgF], [protein|CE4A49F5CCC2D36C5CE5AD7AE7F0A70F2D4F425C|AapA], [protein|1594BA83CED2DA9F86C1CE2A0DC6E1C9B665EACB|GabP], [protein|219586A3F378DC38EA076FD39B99D41136BDE722|YtnA], [protein|423AEC9D260BE53AD22851D999244B89BEB3E84D|HutM]

    • Structure

  • [PDB|3GI9] (from ''M. jannaschii'', 23% identity) [Pubmed|19608859]

    • Expression and Regulation

    Operons

    genes
    [gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|T-box|T-box]: anti-termination, in [regulon|T-box|T-box]

    • regulation:

  • the [SW|T-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]
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    Biological materials

    Mutant

  • MGNA-A468 (yvbW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/468 NBRP B. subtilis, Japan]
  • BKE34010 (Δ[gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE34010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTCTTCTACCTCTCCT, downstream forward: _UP4_TAAATAAGAAACCCTCTTGC
  • BKK34010 (Δ[gene|8C4A8961B2514A8AD531AFB104B10C0797D02AC2|yvbW]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK34010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCTCTTCTACCTCTCCT, downstream forward: _UP4_TAAATAAGAAACCCTCTTGC

    • References

  • 18625071,19608859