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splA [Mon Aug 31 2015 13:54:00 GMT+0200 (CEST)]
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splA [Mon Aug 31 2015 13:54:00 GMT+0200 (CEST)]

transcriptional repressor of the spore photoproduct lyase splA-splB operon
locus
BSU13920
pI
4.42
mw
9.00 kDa
function
regulation of the splA-splB operon
product
transcriptional regulator
essential
no
synonyms
ykxI

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • syns
    ykxI

    [SW|Categories] containing this gene/protein

  • [SW|DNA repair/ recombination], [SW|transcription factors and their control], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigG regulon]
  • Expression and Regulation

    Operon

  • ''[protein|search|splA]-[protein|search|splB]'' [Pubmed|8021181]
  • [SW|Sigma factor]

  • [protein|search|SigG] [Pubmed|15699190,8021181]
  • Regulation

  • expressed during sporulation in the forespore ([protein|search|SigG]) [Pubmed|16497325]
  • Regulatory mechanism

  • negative autoregulation by [protein|search|SplA] [Pubmed|8021181]
  • References

    Reviews

  • 23164663
  • Structure of the spore photoproduct lesion in DNA

  • 24598744
  • Original publications

  • 15699190,8021181,22761404,10629212