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levF [Mon Aug 31 2015 13:55:53 GMT+0200 (CEST)]
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levF [Mon Aug 31 2015 13:55:53 GMT+0200 (CEST)]

fructose-specific phosphotransferase system, EIIC component of the PTS
locus
BSU27050
pI
4.40
mw
27.00 kDa
function
fructose uptake and phosphorylation
product
fructose-specific phosphotransferase system
EIIC component
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.2|Phosphotransferase system] → [category|SW 1.2.2.2|Sugar specific PTS proteins]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.27|Utilization of other polymeric carbohydrates]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.7|Utilization of fructose]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|LevR regulon], [SW|SigL regulon]
  • The protein

    Protein family

  • [SW|PTS] permease, mannose permease (Man) family [Pubmed|10627040]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|LevF]-[protein|search|LevG]
  • Expression and Regulation

    Operon

  • ''[protein|search|levD]-[protein|search|levE]-[protein|search|levF]-[protein|search|levG]-[protein|search|sacC]'' [Pubmed|2117666]
  • [SW|Sigma factor]

  • [protein|search|SigL] [Pubmed|1924373]
  • Regulation

  • subject to carbon catabolite repression ([protein|search|CcpA], [protein|search|LevR]) [Pubmed|7592486]
  • induced in the presence of fructose ([protein|search|LevR]) [Pubmed|1900939]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|7592486]
  • [protein|search|LevR]: transcription activation [Pubmed|1900939]
  • References

  • 10627040,2117666,1924373,7592486,1900939