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atpF [2019-03-01 17:24:09]
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atpF [2019-03-01 17:24:09]

ATP synthase, part of the Fo complex (subunit b)
locus
BSU36850
pI
4.92
mw
19.06 kDa
protein length
170 aa Sequence Blast
gene length
513 bp Sequence Blast
function
ATP synthesis
product
ATP synthase (subunit b))
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.5|ATP synthesis] → [category|SW 2.1.5.1|ATPase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,785,945 3,786,457

    The protein

    Catalyzed reaction/ biological activity

  • ATP synthesis [http://www.youtube.com/watch?v=uOoHKCMAUMc see a video]

    • Protein family

  • ATPase B chain family (according to Swiss-Prot)

    • Effectors of protein activity

  • ATPase activity is inhibited upon binding of Mg-ADP to [protein|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|AtpD] [pubmed|30580998]

    • Structure

  • [PDB|see here an overview on ATPase structure]

    • [SW|Localization]

  • membrane [Pubmed|18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI]-[gene|CC1894D90AC17487A286B2909964916825055F93|atpB]-[gene|6CF7F6303425D8A51E1E01BF18823139E4259A8F|atpE]-[gene|87311FEA265AD3F5526C78D631E7E51BBF01F0D6|atpF]-[gene|E956A30D97B2941108880F3AD48620C4DB6E0EBD|atpH]-[gene|E3FADE979CE6AB6315F67812608FCE00CF4E2453|atpA]-[gene|492EEC8068043DA770F5DC1D54799C4366AE9A01|atpG]-[gene|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|atpD]-[gene|A9DA64F8C7A60E8E2B1EDC99BEA1BD7DD0135AA6|atpC]
    description
    [Pubmed|9353933]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]

    • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • the mRNA is processed between [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI] and [gene|CC1894D90AC17487A286B2909964916825055F93|atpB] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|YmcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|YlbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|YaaT] complex [Pubmed|29794222]
    • view in new tab

    Biological materials

    Mutant

  • BKE36850 ([gene|87311FEA265AD3F5526C78D631E7E51BBF01F0D6|atpF]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTACTACGGCAACTCCC, downstream forward: _UP4_CGATGAGTGGATCAGCTGTC
  • BKK36850 ([gene|87311FEA265AD3F5526C78D631E7E51BBF01F0D6|atpF]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTACTACGGCAACTCCC, downstream forward: _UP4_CGATGAGTGGATCAGCTGTC

    • References

    Reviews

  • 23356252,23341301,23267178,22822068,21524994,19489730,17208001,16730323

    • Original publications

  • 7961438,18763711,30580998