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fruR
transcription repressor of the [gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]-[gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]-[gene|973C3D3FBFDCA095A760C5F49A96D8BE48771014|fruA] operon, [SW|DeoR family]
function
regulation of fructose utilization
product
transcription repressor
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.7|Utilization of fructose][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]Gene
Coordinates
1,507,578 1,508,333
The protein
[SW|Domains]
[SW|HTH deoR-type domain] (aa 3-58) (according to UniProt)Expression and Regulation
Operons
genes
[gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]-[gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]-[gene|973C3D3FBFDCA095A760C5F49A96D8BE48771014|fruA]
description
[pubmed|22383849]
regulatory mechanism
[protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR]: repression, (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]), in [regulon|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR regulon]regulation
induced in the presence of fructose ([protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR]) (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])view in new tabBiological materials
Mutant
BKE14380 ([gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTTCACCTCCTAATGA, downstream forward: _UP4_ACTGTCGTAAAGGTAGTGAABKK14380 ([gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTTCACCTCCTAATGA, downstream forward: _UP4_ACTGTCGTAAAGGTAGTGAAReferences