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acdA [Fri Nov 13 2015 18:52:23 GMT+0100 (CET)]
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acdA [Fri Nov 13 2015 18:52:23 GMT+0100 (CET)]

acyl-CoA dehydrogenase
locus
BSU37170
pI
4.00
mw
41.00 kDa
function
fatty acid degradation
product
acyl-CoA dehydrogenase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.3|Utilization of fatty acids]

    • [SW|Categories] containing this gene/protein

  • [SW|utilization of lipids], [SW|sporulation proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|FadR regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,813,246 -> 3,814,385

    The protein

    Catalyzed reaction/ biological activity

  • Acyl-CoA ETF = 2,3-dehydroacyl-CoA reduced ETF (according to Swiss-Prot)

    • Protein family

  • acyl-CoA dehydrogenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|YngJ], [protein|search|MmgC], [protein|search|FadE]

    • Structure

  • [PDB|2Z1Q] (from ''Thermus thermophilus hb8'', 40% identity, 55% similarity)

    • Expression and Regulation

    Operon

  • ''[protein|search|fadF]-[protein|search|acdA]-[protein|search|rpoE]'' [Pubmed|17189250]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|17189250]

    • Regulation

  • repressed in the absence of long-chain fatty acids ([protein|search|FadR]) [Pubmed|17189250]

    • Regulatory mechanism

  • [protein|search|FadR]: transcription repression [Pubmed|17189250]

    • References

  • 17189250,17919287