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pbuX [Mon Aug 31 2015 13:55:12 GMT+0200 (CEST)]
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pbuX [Mon Aug 31 2015 13:55:12 GMT+0200 (CEST)]

xanthine transport in/out via proton symport
locus
BSU22060
pI
8.79
mw
46.00 kDa
function
xanthine uptake
product
xanthine permease
essential
no
synonyms
ypaQ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.6|Nucleotide/ nucleoside transporter]
  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.1|Biosynthesis/ acquisition of purine nucleotides]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
    • syns
    ypaQ

    [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|biosynthesis/ acquisition of nucleotides], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|G-box], [SW|PurR regulon]

    • The protein

    [SW|Localization]

  • membrane [Pubmed|18763711]

    • Expression and Regulation

    Operon

  • ''[protein|search|xpt]-[protein|search|pbuX]'' [Pubmed|9098051]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9098051]

    • Regulation

  • repressed in the presence of adenine or adenosine ([protein|search|PurR]) [Pubmed|11591660]
  • induced in the absence of guanine ([protein|search|G-box]) [Pubmed|12787499]

    • Regulatory mechanism

  • [protein|search|G-box]: transcription termination/ antitermination ([SW|riboswitch]) [Pubmed|9098051,12787499]
  • [protein|search|PurR]: transcription repression (molecular inducer: PRPP) [Pubmed|11591660]

    • References

  • 12923093,11591660,9098051,11591660,18763711