membrane-anchored protein quality control protease, serine protease, response to secretion and heat stresses
function
protein quality control
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.1|Protein quality control][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|proteolysis], [SW|heat shock proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|CssR regulon]Gene
Coordinates on the chromosome (coding sequence)
3,384,070 -> 3,385,446
The protein
Protein family
peptidase S1B family (according to Swiss-Prot)Structure
[PDB|3QO6] (from ''Arabidopsis thaliana'', 38% identity) [Pubmed|21532594][SW|Localization]
cell membrane (according to Swiss-Prot)randomly distributed in foci throughout the cell surface [Pubmed|22307758]Expression and Regulation
Operon
''htrB'' (according to [http://dbtbs.hgc.jp/COG/prom/yvtA.html DBTBS])Regulation
expressed under conditions of secretion stress ([protein|search|CssR]) [Pubmed|12270824]induced by rhamnolipids [Pubmed|22092710]Regulatory mechanism
[protein|search|CssR]: transcription activation [Pubmed|12270824]Additional information
[protein|search|HtrB] is subject to degradation by [protein|search|WprA] and other extracellular proteases [PubMed|24362423]References
Reviews
22688815,21326199,25212246 Original publications
17600057,22307758,12270824,22092710,24362423,24115457,11133960,21532594 
