glycine betaine/carnitine/choline ABC transporter (ATP-binding protein)
function
compatible solute transport
product
glycine betaine/carnitine/choline
ABC transporter (ATP-binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.4|Uptake of compatible solutes for osmoprotection][category|SW 3|Information processing] → [category|SW 3.5|Targets of second messengers] → [category|SW 3.5.1|Targets of c-di-AMP][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|coping with hyper-osmotic stress], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|OpcR regulon], [SW|RemA regulon]Gene
Coordinates on the chromosome (coding sequence)
3,469,860 -> 3,471,002
The protein
Protein family
[SW|ABC transporter] family (according to Swiss-Prot)Paralogous protein(s)
[SW|OpuBA][SW|Domains]
2 [SW|CBS domain]s (255-314, 315-373)[SW|Localization]
associated to the membrane (via [SW|OpuCB]-[SW|OpuCD]) [Pubmed|10092453,18763711][SW|Interactions]
[SW|OpuCA]-([SW|OpuCB]-[SW|OpuCD])-[SW|OpuCC] [Pubmed|10092453]Expression and Regulation
Operon
''[SW|opuCA]-[SW|opuCB]-[SW|opuCC]-[SW|opuCD]'' [Pubmed|10216873]Regulation
induced by salt stress [Pubmed|23960087,10216873]repressed by choline ([protein|search|OpcR]) [Pubmed|23960087]Regulatory mechanism
[protein|search|OpcR]: transcription repression [Pubmed|23960087][protein|search|RemA]: transcription activation [Pubmed|23646920]Biological materials
Expression vector
pGP2939 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s labReferences
10092453,9925583,10216873,18763711,21296969,23960087,23646920 
