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mhqA [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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mhqA [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone
locus
BSU12870
pI
5.00
mw
35.00 kDa
function
resistence to methyl-hydroxyquinone
product
hydroquinone-specific dioxygenase
essential
no
synonyms
ykcA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

    • [SW|Categories] containing this gene/protein

  • [SW|resistance against oxidative and electrophile stress]

    • This gene is a member of the following [SW|regulons]

  • [SW|MhqR regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,353,080 -> 1,354,030

    The protein

    Protein family

  • extradiol ring-cleavage dioxygenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|MhqE], [protein|search|MhqO]

    • Structure

  • [PDB|3OAJ] ([protein|search|MhqO], 34% identical residues)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''mhqA'' [Pubmed|17725564]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|17725564]

    • Regulation

  • induced by catechol and 2-methylhydroquinone ([protein|search|MhqR]) [Pubmed|17725564]

    • Regulatory mechanism

  • [protein|search|MhqR]: transcription repression [Pubmed|17725564]

    • Biological materials

    Mutant

  • MGNA-A737 (ykcA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/737 NBRP B. subtilis, Japan]

    • References

  • 17407181,17725564