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yisV [2019-05-10 10:33:38]
similar to transcriptional regulator ([SW|MocR/ GabR family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]Gene
Coordinates
1,166,737 1,168,191
The protein
Protein family
[SW|MocR/ GabR family] [Pubmed|22020104][SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to Swiss-Prot)Paralogous protein(s)
[protein|B1A95EAE40AFA40BF12EE9B41287921417A39562|YdfD] [SW|Domains]
N-terminal DNA-binding helix-turn-helix motif; C-terminal domain is homologous to PLP-binding large domain of aminotransferases.[SW|Cofactors]
PLPStructure
[PDB|1WST] (aminotransferase from Thermococcus profundus, 29% identity)Expression and Regulation
Operons
genes
[gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B211 (yisW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1210 NBRP B. subtilis, Japan]BKE10880 ([gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCCCTTTTTTACAC, downstream forward: _UP4_CGCCTGATGATGTCCTAGGCBKK10880 ([gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCCCTTTTTTACAC, downstream forward: _UP4_CGCCTGATGATGTCCTAGGCReferences