SubtiBank SubtiBank
yisV
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yisV

similar to transcriptional regulator ([SW|MocR/ GabR family])
locus
BSU_10880
pI
9.30
mw
54.11 kDa
protein length
484 aa Sequence Blast
gene length
1455 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
yisW
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]

    • Gene

    Coordinates
    1,166,737 1,168,191

    The protein

    Protein family

  • [SW|MocR/ GabR family] [Pubmed|22020104]
  • [SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|B1A95EAE40AFA40BF12EE9B41287921417A39562|YdfD]

    • [SW|Domains]

  • N-terminal DNA-binding helix-turn-helix motif; C-terminal domain is homologous to PLP-binding large domain of aminotransferases.
  • [SW|HTH gntR-type domain] (aa 14-82) (according to UniProt)

    • [SW|Cofactors]

  • PLP

    • Structure

  • [PDB|1WST] (aminotransferase from Thermococcus profundus, 29% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]
    description
    [pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-B211 (yisW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1210 NBRP B. subtilis, Japan]
  • BKE10880 ([gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCCCTTTTTTACAC, downstream forward: _UP4_CGCCTGATGATGTCCTAGGC
  • BKK10880 ([gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCCCTTTTTTACAC, downstream forward: _UP4_CGCCTGATGATGTCCTAGGC

    • References

  • 11756427,22020104