SubtiBank SubtiBank
yngB
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yngB

similar to UTP-glucose-1-phosphate uridylyltransferase
locus
BSU_18180
pI
5.20
mw
32.99 kDa
protein length
297 aa Sequence Blast
gene length
894 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.6|Cell wall/ other/ based on similarity]

    • Gene

    Coordinates
    1,946,702 1,947,595

    The protein

    Catalyzed reaction/ biological activity

  • α-D-glucose 1-phosphate + H+ + UTP --> diphosphate + UDP-α-D-glucose (according to UniProt)

    • Protein family

  • UDPGP type 2 family (with [protein|D368988F85D8436DD424B0B4A1591BDF092A8EA7|GtaB] and [protein|FC455B727F66632D94D93E103B30748944ED04A0|YtdA], according to UniProt)

    • Paralogous protein(s)

  • [protein|D368988F85D8436DD424B0B4A1591BDF092A8EA7|GtaB], [protein|FC455B727F66632D94D93E103B30748944ED04A0|YtdA]

    • Structure

  • [PDB|5I1F] (from Burkholderia vietnamiensis, 50% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]-[gene|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB]-[gene|289828D37CF5422908316ED2EF1AEAE76F84161D|yngC]
    description
    [Pubmed|20512483]

    sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]

    • regulatory mechanism

  • [protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon]

    • regulation

  • expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
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    Biological materials

    Mutant

  • MGNA-B396 (yngB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1395 NBRP B. subtilis, Japan]
  • BKE18180 ([gene|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTCACTTTTTTTCTCATTC, downstream forward: _UP4_TAAAAAAATTGTAACCATCT
  • BKK18180 ([gene|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTCACTTTTTTTCTCATTC, downstream forward: _UP4_TAAAAAAATTGTAACCATCT

    • References

  • 20512483