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ytzG
similar to 16S pseudouridylate synthase
function
16S rRNA modification
product
putative 16S pseudouridylate synthase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.3|rRNA modification and maturation/ based on similarity]Gene
Coordinates
3,072,743 3,073,462
The protein
Catalyzed reaction/ biological activity
uridine516 in 16S rRNA --> a pseudouridine516 in 16S rRNA (according to E. coli RsuA)Protein family
[SW|S4 RNA-binding domain] superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)pseudouridine synthase RsuA family (with [protein|5CD1E266B0EC82546A2AF19A05490DD4D04F812C|RluB], according to UniProt)[SW|Domains]
[SW|S4 RNA-binding domain] (aa 1-65) (according to UniProt)Structure
[PDB|1KSK] (RsuA from E. coli, 40% identical) [pubmed|11953756]Expression and Regulation
Operons
genes
[gene|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ]-[gene|69052B24B577ABA4B20E610F679154DC97EFD8DE|ytzG]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE30035 ([gene|69052B24B577ABA4B20E610F679154DC97EFD8DE|ytzG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE30035 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCCAATCTCTCCTTTA, downstream forward: _UP4_TGACAAAAACCCCGCATACCBKK30035 ([gene|69052B24B577ABA4B20E610F679154DC97EFD8DE|ytzG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK30035 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCCAATCTCTCCTTTA, downstream forward: _UP4_TGACAAAAACCCCGCATACCReferences
