iron storage protein, DNA-binding stress protein, forms highly stable, multimeric protein-DNA complexes which protect against oxidative killing
product
mini-ferritin, DNA-binding stress protein
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.3|Acquisition of iron / Other][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.1|Acquisition of iron / Other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress][SW|Categories] containing this gene/protein
[SW|acquisition of iron], [SW|iron metabolism], [SW|resistance against oxidative and electrophile stress]This gene is a member of the following [SW|regulons]
[SW|PerR regulon]The protein
Catalyzed reaction/ biological activity
forms highly stable, multimeric protein-DNA complexes which protect against oxidative killingProtein family
dps family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|Dps][SW|Cofactors]
contains an iron-sulfur clusterStructure
[PDB|2CHP]Expression and Regulation
Operon
''mrgA'' [Pubmed|8396117][SW|Sigma factor]
[protein|search|SigA] [Pubmed|14563870]Regulation
induced by hydrogen peroxide ([protein|search|PerR]) [Pubmed|11532148]Regulatory mechanism
[protein|search|PerR]: transcription repression [Pubmed|11532148]References
Reviews
Original publications
9393687,14563870,7667267,12486061,8396117,9393707,8709848,8932315,11532148