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tagG
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tagG

[SW|ABC transporter] for teichoic acid translocation (permease)
locus
BSU_35710
pI
9.56
mw
32.03 kDa
protein length
275 aa Sequence Blast
gene length
828 bp Sequence Blast
function
[category|SW 2.6.1.3|Biosynthesis of teichoic acid]
product
[SW|ABC transporter] for teichoic acid translocation (permease)
essential
yes
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid]
  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.6|Export of anionic polymers and attachment to peptidoglycan]
  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.4|Export of cell wall components]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,675,167 3,675,994

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Protein family

  • [SW|ABC-2 integral membrane protein family] (according to UniProt)

    • [SW|Domains]

  • [SW|ABC transmembrane type-2 domain] (aa 35-267) (according to UniProt)

    • Structure

  • [PDB|6JBH] (the complex corresponding to [protein|6795F1703416DCD04E51C177F1C9FE45E73ABAEF|TagG]-[protein|4D3C316965834130BB378CBD1265CFA13F086C7A|TagH] from Alicyclobacillus herbarius, 41.7% identity) [pubmed|32184247]

    • [SW|Localization]

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|8620DA76A1953D7ACDFA7E46ED81EF1A0D97999C|tagD]-[gene|88028A5F3520CB6DAB014412974EB59CC5D226DD|tagE]-[gene|E730E41546298960A4B907FCB7F36C495AA9602B|tagF]-[gene|6795F1703416DCD04E51C177F1C9FE45E73ABAEF|tagG]-[gene|4D3C316965834130BB378CBD1265CFA13F086C7A|tagH]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|7581998], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP]: repression, [Pubmed|9457886], in [regulon|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP regulon]
  • [protein|7F340423A34CE40D1F1AA8D373F7C4B859A6496D|WalR]: activation, [Pubmed|12950927], in [regulon|7F340423A34CE40D1F1AA8D373F7C4B859A6496D|WalR regulon]

    • regulation

  • repressed by phosphate ([protein|search|PhoP]) [Pubmed|9457886]
    • view in new tab

    Biological materials

    GFP fusion

  • 3512 [gene|0467447B10EE7C1FDF86022AB6FBDBABFD32A9E5|trpC]2 [gene|6795F1703416DCD04E51C177F1C9FE45E73ABAEF|tagG]::pSG5322 (cat Pxyl-gfp-[gene|6795F1703416DCD04E51C177F1C9FE45E73ABAEF|tagG]1-346) [pubmed|18156271], available in [SW|Dirk Jan Scheffers]' lab and in the [http://bgsc.org BGSC]

    • References

    Reviews

  • 24024634

    • Original publications

  • 18156271,10092453,7565096,21280653,22383849,32184247