riboflavin ECF transporter, S protein
function
riboflavin uptake
product
S protein of riboflavin ECF transporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.3|ECF transporter][category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.3|ECF transporter] → [category|SW 1.2.3.2|The substrate-specific S components of the ECF transporters][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.2|Biosynthesis/ acquisition of riboflavin/ FAD][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ECF transporter], [SW|biosynthesis of cofactors], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|FMN-box]Gene
Coordinates on the chromosome (coding sequence)
2,410,017 -> 2,410,589
The protein
Structure
[PDB|3P5N] (RibU from ''Staphylococcus aureus'')[SW|Localization]
membrane[SW|Interactions]
[protein|search|YbaF]-[protein|search|RibU] [Pubmed|20497229]Expression and Regulation
Operon
''[protein|search|ribU]'' [Pubmed|21815947]there is a promoter directly in front of ''[protein|search|ribU]'' [Pubmed|17693491]Regulation
expressed in the absence of FMN ([protein|search|FMN-box]) [Pubmed|17693491]Regulatory mechanism
[protein|search|FMN-box]: [SW|riboswitch], sequestration of the Shine-Dalgarno sequence in the presence of FMN or FMNH2, this is counter-acted upon binding of [SW|RibR] [Pubmed|26494285] [Pubmed|12456892]Additional information
the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] [PubMed|21815947]References
Reviews
20497229,22574898,24362466 Original publications
12456892,20972419,17693491,21815947,24356467,24755604,25438558,26494285,27312125 
