transcriptional repressor (GntR family) of the gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG operon
function
regulation of glucomannan utilization
product
transcriptional repressor (GntR family)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.25|Utilization of glucomannan][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|transcription factors and their control]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|CcpA regulon], [SW|GmuR regulon]Gene
Coordinates on the chromosome (coding sequence)
630,170 -> 630,883
The protein
Protein family
[SW|GntR family] of transcription factorsStructure
[PDB|2WV0] (the structure of [SW|NagR], 29% identity) [Pubmed|20047956]Expression and Regulation
Operon
''[protein|search|gmuB]-[protein|search|gmuA]-[protein|search|gmuC]-[protein|search|gmuD]-[protein|search|gmuR]-[protein|search|gmuE]-[protein|search|gmuF]-[protein|search|gmuG]'' [Pubmed|18177310][SW|Sigma factor]
[protein|search|SigA] [Pubmed|18177310]Regulation
induced by conjac glucomannan (requires [protein|search|GmuG]) ([protein|search|GmuR]) [Pubmed|18177310]induced by cellobiose ([protein|search|GmuR]) [Pubmed|18177310]subject to carbon catabolite repression ([protein|search|CcpA]) [Pubmed|18177310]Regulatory mechanism
[protein|search|GmuR]: transcription repression [Pubmed|18177310][protein|search|CcpA]: transcription repression [Pubmed|18177310][protein|search|AbrB]: transcription activation [Pubmed|20817675]References
18177310,10627040,18177310,20817675,20047956 
