similar to H+/glutamate symporter, minor glyphosate transporter
product
similar to H+/glutamate symporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.6|Dicarboxylate/amino acid:cation symporter][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
253,518 254,762
The protein
Catalyzed reaction/ biological activity
uptake of glyphosate [pubmed|30666812]Protein family
[SW|dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family] (according to UniProt)Paralogous protein(s)
[protein|107DDCC7B6AA2D7CB02E53F043A93CF05C679081|DctP], [protein|533EEB1A454D29800C9A00A0BE107ECEE2138DAB|GltT] Structure
[PDB|4KY0] the glutamate transporter of ''Thermococcus kodakarensis'', 33% identity, 68% similarity) [Pubmed|24013209][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
ADB1 ([gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]::neo trpC2 pheA1 available in [SW|Erhard Bremer]'s and [SW|Jörg Stülke]'s labs [Pubmed|25344233]BP234 (''[gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]''::''cat''), available in [SW|Fabian Commichau]'s labBP235 (''[gene|533EEB1A454D29800C9A00A0BE107ECEE2138DAB|gltT]''::''spc ''''[gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]''::''cat''), available in [SW|Fabian Commichau]'s labBKE02340 ([gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATGAATCCCCCTTTAGA, downstream forward: _UP4_TAGAAAAAAAGAACACCTCABKK02340 ([gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATGAATCCCCCTTTAGA, downstream forward: _UP4_TAGAAAAAAAGAACACCTCAMDB52 ([gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]::cat trpC2 pheA1 available in [SW|Erhard Bremer]'s and [SW|Jörg Stülke]'s labs [Pubmed|25344233]GP2799 (''Δ''''[gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]''::''kan''), available in [SW|Jörg Stülke]'s lab [pubmed|32743959]GP2824 (''Δ''''[gene|622856EE642C42247C658DBD57E6A18C6E81FE58|gltP]''::''cat''), available in [SW|Jörg Stülke]'s labReferences
7751298,21821766,24013209,25344233,30666812