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nusB [2018-07-20 09:44:34]
probable transcription termination
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.3|Transcription elongation/ termination]Gene
Coordinates
2,529,267 → 2,529,662
The protein
Protein family
nusB family (according to Swiss-Prot)Expression and Regulation
Operons
genes
[gene|6155468AFF216D97373CEF7B8C6E6C7BB9D4617F|nusB]-[gene|71FC6E75694B7066D808BAD736140569875E5E5C|folD]
description
[Pubmed|2536750,11591660]
regulatory mechanism
[protein|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|PurR]: repression, (molecular inducer: PRPP) [Pubmed|2536750,11591660], in [regulon|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C|PurR regulon][regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]regulation
repressed in the presence of purine nucleotides ([protein|search|PurR]) [Pubmed|2536750,11591660]view in new tabBiological materials
Mutant
MGNA-C368 (yqhZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2366 NBRP B. subtilis, Japan]BKE24320 (Δ[gene|6155468AFF216D97373CEF7B8C6E6C7BB9D4617F|nusB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTTTCTCCTTTGAT, downstream forward: _UP4_TAGGAGGAAAGAAAATGACTBKK24320 (Δ[gene|6155468AFF216D97373CEF7B8C6E6C7BB9D4617F|nusB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTTTCTCCTTTGAT, downstream forward: _UP4_TAGGAGGAAAGAAAATGACTReferences
11948165,16707701,11591660,2536750