SubtiBank SubtiBank
rluB [2017-8-11 16:0:3]
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rluB [2017-8-11 16:0:3]

pseudouridine synthase
locus
BSU23160
pI
10.25
mw
25.88 kDa
protein length
229 aa Sequence Blast
gene length
687 bp Sequence Blast
function
23S rRNA modification
product
pseudouridine synthase
essential
no
ec
5.4.99.22
synonyms
ypuL

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.2|rRNA modification and maturation]
  • Gene

    Coordinates
    2,421,438 → 2,422,172

    The protein

    Catalyzed reaction/ biological activity

  • rRNA uridine = rRNA pseudouridine (according to Swiss-Prot)
  • Protein family

  • pseudouridine synthase rsuA family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|YtzF]
  • Structure

  • [PDB|4LAB] (from ''E. coli'', 40% identity) [Pubmed|24214967]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|5CD1E266B0EC82546A2AF19A05490DD4D04F812C|rluB]-[gene|F7D869F77E2275110737EF658C58FA1BF742D73F|resA]-[gene|495721E4B8BF6FEC01E62E86339560F90776EED1|resB]-[gene|97FE84CF968596AC39D19EE2E43DA625147FD702|resC]-[gene|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]-[gene|EA6790EF30D3DDB9670FE52DFD2C5083AB6A48E1|resE]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A106 (ypuL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/106 NBRP B. subtilis, Japan]
  • References

  • 9888802,24214967