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yjcG
function
nucleotide metabolism
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.4|Nucleotide metabolism/ other][category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
1,256,862 1,257,377
The protein
Catalyzed reaction/ biological activity
hydrolyzes a 2´,3´-cyclic nucleotide, thereby producing a nucleotide with a 3´-phosphate [pubmed|31422053]Protein family
2H phosphoesterase superfamily (with [protein|29A38D244A07ED0973D0846B652238524F4DBC67|YtlP], according to UniProt) [pubmed|31422053]Paralogous protein(s)
[protein|29A38D244A07ED0973D0846B652238524F4DBC67|YtlP] Structure
[PDB|2D4G]Expression and Regulation
Operons
genes
[gene|94EE92D99CA68856E6D19254B0768FFE92AF603D|yjcH]-[gene|5CA17CD28A725B8D7B87B9AAA167844042439794|yjcG]-[gene|5E4C3ADF5B5D0215E9E350F16BCA57B208933606|yjcF]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B255 (yjcG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1254 NBRP B. subtilis, Japan]BKE11850 ([gene|5CA17CD28A725B8D7B87B9AAA167844042439794|yjcG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATGTCCCTCCTGGA, downstream forward: _UP4_TTGCTAGGCAGAGGAGAATABKK11850 ([gene|5CA17CD28A725B8D7B87B9AAA167844042439794|yjcG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATGTCCCTCCTGGA, downstream forward: _UP4_TTGCTAGGCAGAGGAGAATAReferences
12107147,18473364,16511078,31422053