ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin, as well as for the siderophores schizokinen and arthrobactin (ATPase)
function
acquisition of iron
product
ABC transporter for the siderophores Fe-enterobactin,
Fe-bacillibactin, schizokinen and arthrobactin (ATPase)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores][category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|Fur regulon]Gene
Coordinates on the chromosome (coding sequence)
3,379,112 -> 3,379,939
The protein
Catalyzed reaction/ biological activity
ATPase for the [protein|search|FeuA]-[protein|search|FeuB]-[protein|search|FeuC] siderophore [SW|ABC transporter] and for the [protein|search|YfhA]-[protein|search|YfiY]-[protein|search|YfiZ] siderophore [SW|ABC transporter]Protein family
[SW|ABC transporter] family (according to Swiss-Prot)Structure
[PDB|4R9U], the ''E. coli'' BtuC-BtuD complex, BtuD shares 32% identity, 57% similarity with YusV, [Pubmed|25402482][SW|Localization]
associated to the membrane (via [protein|search|FeuB]-[protein|search|FeuC] and [protein|search|YfhA]-[protein|search|YfiZ]) [Pubmed|10092453][SW|Interactions]
[protein|search|YusV]-([protein|search|FeuB]-[protein|search|FeuC])-[protein|search|FeuA] [Pubmed|10092453][protein|search|YusV]-([protein|search|YfhA]-[protein|search|YfiZ])-[protein|search|YfiY] [Pubmed|10092453]Expression and Regulation
Regulation
induced upon iron starvation ([protein|search|Fur]) [Pubmed|12354229]Regulatory mechanism
[protein|search|Fur]: transcription repression [Pubmed|12354229]Additional information
the terminator is [protein|search|NusA]-dependent [ http://www.nature.com/articles/nmicrobiol20157 Reference]References
19746494,10092453,16672620,12354229,25402482 
