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kipI [Mon Aug 31 2015 13:52:30 GMT+0200 (CEST)]
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kipI [Mon Aug 31 2015 13:52:30 GMT+0200 (CEST)]

inhibitor of KinA, control of the phosphorelay
locus
BSU04080
pI
4.66
mw
26.00 kDa
function
control of the phosphorelay, initiation of sporulation
product
inhibitor of KinA
essential
no
synonyms
ycsJ

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.2|Proteins controlling the activity of the kinases]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.2|Proteins controlling the activity of the kinases]
  • syns
    ycsJ

    [SW|Categories] containing this gene/protein

  • [SW|phosphorelay]
  • This gene is a member of the following [SW|regulons]

  • [SW|KipR regulon], [SW|TnrA regulon]
  • The protein

    Effectors of protein activity

  • binding of [protein|search|KipA] prevents [protein|search|KipI] from binding to [protein|search|KinA] [Pubmed|9334321]
  • Structure

  • [PDB|2ZP2] [Pubmed|18823995]
  • [SW|Interactions]

  • [protein|search|KipI]-[protein|search|KinA] [Pubmed|9334321], [protein|search|KipI]-[protein|search|KipA] [Pubmed|9334321]
  • Expression and Regulation

    Operon

  • ''[protein|search|ycsF]-[protein|search|ycsG]-[protein|search|ycsI]-[protein|search|kipI]-[protein|search|kipA]-[protein|search|kipR]-[protein|search|lipC]'' [Pubmed|9334321]
  • Regulatory mechanism

  • [protein|search|KipR]: transcription repression [Pubmed|9334321]
  • [protein|search|TnrA]: transcription activation [Pubmed|9334321]
  • References

  • 9334321,20524093,18823995,21050859,25755103