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fisB [2017-8-11 16:0:3]
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fisB [2017-8-11 16:0:3]

membrane fission protein, mediates membrane fission during sporulation
locus
BSU32350
pI
9.53
mw
27.76 kDa
protein length
254 aa Sequence Blast
gene length
762 bp Sequence Blast
function
release of the forespore into the mother cell cytoplasm
product
membrane fission protein
essential
no
synonyms
yunB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.7|Membrane dynamics]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,322,463 → 3,323,227

    Phenotypes of a mutant

  • reduced sporulation efficiency (12 - 15%) [Pubmed|23388828]

    • The protein

    Catalyzed reaction/ biological activity

  • mediates membrane fission during [SW|sporulation] [Pubmed|23388828]
  • binds cardiolipin [Pubmed|23388828]

    • [SW|Localization]

  • cell membrane [Pubmed|23388828]
  • forms dynamic foci which become immobilized at the site of membrane fission [Pubmed|23388828]

    • Expression and Regulation

    Operons

    genes
    [gene|588A4131772691A0402AD56B49D5C55D8BD46DFF|fisB]
    description
    [Pubmed|12662922]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,12662922], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulation

  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,12662922]
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    Biological materials

    Mutant

  • MGNA-A978 (yunB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/978 NBRP B. subtilis, Japan]

    • References

    Reviews

  • 23518060

    • Original publications

  • 12662922,15699190,23388828