RNA polymerase sigma factor SigB
function
general stress response
product
RNA polymerase sigma factor SigB
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][SW|Categories] containing this gene/protein
[SW|transcription], [SW|sigma factors and their control], [SW|general stress proteins (controlled by SigB)]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|SigB regulon]Gene
Coordinates on the chromosome (coding sequence)
522,862 -> 523,650
The protein
Protein family
SigB subfamily (according to Swiss-Prot)[SW|Interactions]
[protein|search|SigB]-[protein|search|RsbW] [Pubmed|12270815][protein|search|SigB]-[protein|search|RpoB]-[protein|search|RpoC]Expression and Regulation
Operon
''[protein|search|rsbR]-[protein|search|rsbS]-[protein|search|rsbT]-[protein|search|rsbU]-[protein|search|rsbV]-[protein|search|rsbW]-[protein|search|sigB]-[protein|search|rsbX]'' [Pubmed|8002610]''[protein|search|rsbV]-[protein|search|rsbW]-[protein|search|sigB]-[protein|search|rsbX]'' [Pubmed|2170324][SW|Sigma factor]
''[protein|search|rsbR]'': [protein|search|SigA] [Pubmed|8002610]''[protein|search|rsbV]:'' [protein|search|SigB] [Pubmed|11544224]Regulation
''[protein|search|rsbV]:'' induced by stress ([protein|search|SigB]) [Pubmed|11544224]Biological materials
Mutant
QB5344 (cat), available in the [SW|Stülke] lab1A675 ( ''sigB''::''cat''), [Pubmed|3027048], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A675&Search=1A675 BGSC]1A777 ( ''sigB''::''cat''), [Pubmed|1744042], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A777&Search=1A777 BGSC]1A780 ( ''sigB''::''spec''), [Pubmed|8253681], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A780&Search=1A780 BGSC]Labs working on this gene/protein
[SW|Bill Haldenwang], San Antonio, USA[SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]References
Reviews
19575568,18035607,11407115,9767581,20658979 Control of SigB activity by protein-protein interactions
11377871,12270815,15312768,8460143,8682769,8002610,11591687,7601843,17498739,15342582 Identification of the SigB regulon
11544224,11532142,11717291,10482513,10220166,22174379 Other publications
23407164,22511268,22210769,23524614,21979936,8655572,3123466,10369900,3112122,8468294,8458834,13129942,6784117,12867438,3100810,8253681,12486038,8764398,3027048,15342585,17575448,17586624,23934352,25652417,3016731,11902719,14651641,10503549,15205443,6405278,10383961,15805528,6790515,116131,39767581,19948797,22582280,24572018,24878601 
