major high-affinity Na -coupled glutamate/ aspartate symport protein
function
glutamate and aspartate uptake
product
major Na -coupled glutamate/ aspartate symport protein
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.1|Solute:sodium symporter family][category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.6|Dicarboxylate/amino acid:cation symporter][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|biosynthesis/ acquisition of amino acids], [SW|glutamate metabolism], [SW|utilization of amino acids], [SW|membrane proteins]Gene
Coordinates on the chromosome (coding sequence)
1,096,560 -> 1,097,849
Phenotypes of a mutant
impaired uptake of glutamate and aspartate [Pubmed|25344233]The protein
Protein family
View classification (according to Swiss-Prot)Paralogous protein(s)
[protein|search|GltP], [protein|search|DctP]Structure
[PDB|4IZM] (the protein from ''Pyrococcus horikoshii'', 35% identity, 73% similarity) [Pubmed|23563139][http://pdb.org/pdb/explore/explore.do?structureId=4KY0 4KY0] (the glutamate transporter of ''Thermococcus kodakarensis'', 35% identity, 72% similarity) [Pubmed|24013209][SW|Localization]
cell membrane [Pubmed|18763711]Expression and Regulation
Operon
''gltT'' [Pubmed|22383849]Biological materials
Mutant
available in [SW|Erhard Bremer]'s lab [Pubmed|25344233]References
18763711,23563139,22383849,24013209,25344233 
