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yabN
similar to nucleoside triphosphate pyrophosphohydrolase
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]Gene
Coordinates
66,405 67,874
The protein
[SW|Domains]
contains a domain similar to ''E. coli'' [http://ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG10572 ''mazG''] (nucleoside pyrophosphohydrolase) at the C-terminus (aa 240-480)Structure
[PDB|3CRA] (E. coli MazG, corresponds to the C-terminal domain, aa 238 ... 486), 43.6% identity [pubmed|18353782]Expression and Regulation
Operons
genes
[gene|D6B1837075ECBEE1FEAC704DDB6795336092897F|yabM]-[gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]-[gene|B0CB19A3E3E84E12BF42BB050394C8A059A89359|yabO]-[gene|035B5486A3887FC71ACC0A8FB43ED77DC44E12EA|yabP]-[gene|4DEDB27C0162409571AB4A1BB17CFE400764AE45|yabQ]-[gene|FE0E60B875E72AEF5174A89C7AE5556FF59B19D5|divIC]-[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]
description
[Pubmed|11283287]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon][protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,11283287], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon][protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|12207695], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon][protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|26577401], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon][protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|SigX]: sigma factor, [Pubmed|12207695], in [regulon|E77364F274A520FCCA9F5C9504E317B047BA29E6|SigX regulon]regulation
expressed during sporulation ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]) [Pubmed|11283287]view in new tabBiological materials
Mutant
MGNA-B915 (yabN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1914 NBRP B. subtilis, Japan]BKE00580 ([gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE00580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCACCAAGTCCGACGACTG, downstream forward: _UP4_GAAACTGAGAGGAGATCATABKK00580 ([gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK00580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCACCAAGTCCGACGACTG, downstream forward: _UP4_GAAACTGAGAGGAGATCATAReferences
11283287,26577401,18353782