SubtiBank SubtiBank
yabN
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yabN

similar to nucleoside triphosphate pyrophosphohydrolase
locus
BSU_00580
pI
4.51
mw
55.94 kDa
protein length
489 aa Sequence Blast
gene length
1470 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]
  • Gene

    Coordinates
    66,405 67,874

    The protein

    [SW|Domains]

  • contains a domain similar to ''E. coli'' [http://ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG10572 ''mazG''] (nucleoside pyrophosphohydrolase) at the C-terminus (aa 240-480)
  • Structure

  • [PDB|3CRA] (E. coli MazG, corresponds to the C-terminal domain, aa 238 ... 486), 43.6% identity [pubmed|18353782]
  • Expression and Regulation

    Operons

    genes
    [gene|D6B1837075ECBEE1FEAC704DDB6795336092897F|yabM]-[gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]-[gene|B0CB19A3E3E84E12BF42BB050394C8A059A89359|yabO]-[gene|035B5486A3887FC71ACC0A8FB43ED77DC44E12EA|yabP]-[gene|4DEDB27C0162409571AB4A1BB17CFE400764AE45|yabQ]-[gene|FE0E60B875E72AEF5174A89C7AE5556FF59B19D5|divIC]-[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]
    description
    [Pubmed|11283287]

    sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]
  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,11283287], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]
  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|12207695], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]
  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|26577401], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]
  • [protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|SigX]: sigma factor, [Pubmed|12207695], in [regulon|E77364F274A520FCCA9F5C9504E317B047BA29E6|SigX regulon]
  • regulation

  • expressed during sporulation ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]) [Pubmed|11283287]
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    Biological materials

    Mutant

  • MGNA-B915 (yabN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1914 NBRP B. subtilis, Japan]
  • BKE00580 ([gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE00580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCACCAAGTCCGACGACTG, downstream forward: _UP4_GAAACTGAGAGGAGATCATA
  • BKK00580 ([gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK00580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCACCAAGTCCGACGACTG, downstream forward: _UP4_GAAACTGAGAGGAGATCATA
  • References

  • 11283287,26577401,18353782