SubtiBank SubtiBank
fruK [Mon Aug 31 2015 13:54:04 GMT+0200 (CEST)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

fruK [Mon Aug 31 2015 13:54:04 GMT+0200 (CEST)]

fructose-1-phosphate kinase
locus
BSU14390
pI
4.89
mw
32.00 kDa
function
fructose utilization
product
fructose-1-phosphate kinase
essential
no
ec
2.7.1.56
synonyms
fruB

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.7|Utilization of fructose]
  • syns
    fruB

    [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|FruR regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate (according to Swiss-Prot)
  • Protein family

  • carbohydrate kinase pfkB family (according to Swiss-Prot)
  • Structure

  • [PDB|3OHR]
  • Expression and Regulation

    Operon

  • ''[protein|search|fruR]-[protein|search|fruK]-[protein|search|fruA]'' (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])
  • Regulation

  • induced in the presence of fructose ([protein|search|FruR]) (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])
  • Regulatory mechanism

  • [protein|search|FruR]: transcription repression (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])
  • strongly induced in response to glucose starvation in M9 medium [Pubmed|23033921]
  • References

  • 10627040,23033921