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fruK [2019-08-01 08:29:09]
fructose-1-phosphate kinase
function
fructose utilization
product
fructose-1-phosphate kinase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.7|Utilization of fructose]Gene
Coordinates
1,508,330 1,509,241
The protein
Catalyzed reaction/ biological activity
ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate (according to Swiss-Prot)Protein family
[SW|carbohydrate kinase PfkB family] (according to UniProt)Structure
[PDB|3OHR]Expression and Regulation
Operons
genes
[gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]-[gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]-[gene|973C3D3FBFDCA095A760C5F49A96D8BE48771014|fruA]
description
[pubmed|22383849]
regulatory mechanism
[protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR]: repression, (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]), in [regulon|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR regulon]regulation
induced in the presence of fructose ([protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR]) (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])view in new tabBiological materials
Mutant
BKE14390 ([gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGATTAAGTGTTACAGTGT, downstream forward: _UP4_CGTCTATAGAGGAGGAAACABKK14390 ([gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGATTAAGTGTTACAGTGT, downstream forward: _UP4_CGTCTATAGAGGAGGAAACAReferences
