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rtp
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rtp

replication terminator protein
locus
BSU_18490
pI
9.78
mw
14.38 kDa
protein length
122 aa Sequence Blast
gene length
369 bp Sequence Blast
function
replication termination
product
replication terminator protein
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • Gene

    Coordinates
    2,017,886 2,018,254

    The protein

    Catalyzed reaction/ biological activity

  • binds to nine termination sites spanning 430 kb of the replication terminus region [Pubmed|9642188]
  • Structure

  • [PDB|1F4K] (complex with DNA), [PDB|1BM9]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • forms a single focus, clusters of foci, or multiple foci spanning the bilobed nucleoid, consistent with the terminus region [Pubmed|25071173]
  • Expression and Regulation

    Operons

    genes
    [gene|4F8E1DEB466D24E13E886BEDB5E3F88226BA9386|rtp]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • BKE18490 ([gene|4F8E1DEB466D24E13E886BEDB5E3F88226BA9386|rtp]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCATATGCACTCCTTCTT, downstream forward: _UP4_TAATAGAAACAAACACCCGG
  • BKK18490 ([gene|4F8E1DEB466D24E13E886BEDB5E3F88226BA9386|rtp]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCATATGCACTCCTTCTT, downstream forward: _UP4_TAATAGAAACAAACACCCGG
  • References

    Reviews

  • 19298368
  • Original publications

  • 7746150,10209741,19820088,2498294,2115089,1784827,7934839,9642188,7476199,10064700,8676392,15657033,10931283,25071173,11313334,31165739