SubtiBank SubtiBank
ywhA
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ywhA

similar to transcriptional regulator ([SW|MarR family])
locus
BSU_37550
pI
8.14
mw
15.73 kDa
protein length
139 aa Sequence Blast
gene length
420 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]

    • Gene

    Coordinates
    3,853,717 3,854,136

    The protein

    [SW|Domains]

  • [SW|HTH marR-type domain] (aa 8-139) (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|CA74CB721842927F67FBC3B5C27D2EE46B30CE1C|thrZ]-[gene|4A3CA47533B217F595E7B600923DA31228B94DA8|ywhA]
    description
    [Pubmed|1379177]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1379177], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [regulon|T-box|T-box]: anti-termination, in [regulon|T-box|T-box]

    • regulation

  • induced by threonine limitation ([SW|T-box]) [Pubmed|19258532]
  • the [SW|T-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]
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    Biological materials

    Mutant

  • MGNA-A517 (ywhA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/517 NBRP B. subtilis, Japan]
  • BKE37550 ([gene|4A3CA47533B217F595E7B600923DA31228B94DA8|ywhA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAATTTCCCCATTTC, downstream forward: _UP4_TAGGGATAATAAAAGCCGGT
  • BKK37550 ([gene|4A3CA47533B217F595E7B600923DA31228B94DA8|ywhA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAATTTCCCCATTTC, downstream forward: _UP4_TAGGGATAATAAAAGCCGGT

    • References

  • 1379177,19258532