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ykgB [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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ykgB [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

6-phosphogluconolactonase, general stress protein
locus
BSU13010
pI
5.00
mw
38.00 kDa
function
pentose phosphate pathway
product
6-phosphogluconolactonase
essential
no
ec
3.1.1.31
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.1|Carbon core metabolism] → [category|SW 2.2.1.3|Pentose phosphate pathway]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]

    • [SW|Categories] containing this gene/protein

  • [SW|general stress proteins (controlled by SigB)], [SW|carbon core metabolism]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigB regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,369,876 -> 1,370,925

    The protein

    Catalyzed reaction/ biological activity

  • 6-phosphogluconolactone --> 6-phosphogluconate (pentose phosphate pathway) [Pubmed|22960854]

    • Protein family

  • cycloisomerase 2 family (according to Swiss-Prot)

    • Structure

  • [PDB|3HFQ] (from ''Lactobacillus plantarum'', 42% identity)

    • Expression and Regulation

    Operon

  • ''[protein|search|ykgA]-[protein|search|ykgB]'' [Pubmed|10482513]

    • [SW|Sigma factor]

  • [protein|search|SigB] [Pubmed|10482513]

    • Regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|10482513]

    • Biological materials

    FLAG-tag construct

  • GP1402 (spc, based on [SW|pGP1331]), available in the [SW|Stülke] lab

    • Antibody

  • **

    • References

  • 10482513,15576773,22960854