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msmX [2017-12-15 10:31:22]
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msmX [2017-12-15 10:31:22]

multiple sugar ABC transporter (ATP-binding protein)
locus
BSU38810
pI
7.39
mw
41.21 kDa
protein length
365 aa Sequence Blast
gene length
1095 bp Sequence Blast
function
maltodextrin and melibiose (probably) uptake
product
multiple sugar ABC transporter (ATP-binding protein)
essential
no
synonyms
yxkG
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.1|Uptake of carbon sources]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.21|Utilization of melibiose]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.23|Utilization of starch/ maltodextrin]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.24|Utilization of galactan]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.26|Utilization of pectin]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,984,133 → 3,985,230

    The protein

    Protein family

  • ABC transporter family (according to Swiss-Prot)

    • [SW|Localization]

  • cell membrane (via [protein|8AF43CA410F3381209196E1B9A4FE66D78020793|AraP]-[protein|AE532A8931D516CC676E765D1D1293E73C335D23|AraQ]) and [protein|EA2DD9892C1128ADCD6C8BC61248EBE45339E6D6|MdxF]-[protein|D72CFFE8ED3EC0280AE92C05A136D66ED1F62251|MdxG] [Pubmed|10092453]

    • Expression and Regulation

    Operons

    genes
    [gene|9EE268C3DC3C0F2F846DAEB2004222B6F841B9EA|yxkF]-[gene|434F6C546F783503A82D390FD238F05025FC1802|msmX]
    description
    [Pubmed|10746760]

    regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|10666464], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]

    • regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
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    Biological materials

    Mutant

  • MGNA-B741 (msmX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1740 NBRP B. subtilis, Japan]
  • BKE38810 (Δ[gene|434F6C546F783503A82D390FD238F05025FC1802|msmX]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTAACATCCCCCTTTGT, downstream forward: _UP4_TAAGATCAAAAAAACCGGAC
  • BKK38810 (Δ[gene|434F6C546F783503A82D390FD238F05025FC1802|msmX]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTAACATCCCCCTTTGT, downstream forward: _UP4_TAAGATCAAAAAAACCGGAC

    • References

  • 10092453,16672620,10746760,16707683,10666464,22900538,27501980