phosphate ABC transporter (ATP-binding protein)
function
high-affinity phosphate uptake
product
phosphate ABC transporter (ATP-binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.6|Uptake of ions][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|phosphate metabolism], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|PhoP regulon]Gene
Coordinates on the chromosome (coding sequence)
2,578,003 -> 2,578,812
The protein
Catalyzed reaction/ biological activity
ATP + H2O + phosphate(Out) = ADP + phosphate + phosphate(In) (according to Swiss-Prot)[SW|Localization]
cell membrane (according to Swiss-Prot)[SW|Interactions]
([SW|PstBA]-[SW|PstBB])-([protein|search|PstA]-[protein|search|PstC])-[protein|search|PstS] [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|pstS]-[protein|search|pstC]-[protein|search|pstA]-[SW|pstBA]-[SW|pstBB]'' [Pubmed|9098050][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9098050]Regulation
expressed under conditions of phosphate limitation (5000-fold induced) ([protein|search|PhoP]) [Pubmed|9098050]Regulatory mechanism
[protein|search|PhoP]-P: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]Additional information
mRNA processing between '[protein|search|pstS]' and '[protein|search|pstC]' to maintain higher concentrations of [protein|search|PstS] relative to other components of the [[ABC transporter]] [PubMed|15289558]Labs working on this gene/protein
[SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]References
15289558,10092453,12897025,10913081,9098050,9098050,9593301 
