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hfq [Fri Sep 02 2016 13:02:37 GMT+0200 (CEST)]
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hfq [Fri Sep 02 2016 13:02:37 GMT+0200 (CEST)]

RNA chaperone
locus
BSU17340
pI
8.00
mw
8.00 kDa
function
unknown
product
RNA chaperone
essential
no
synonyms
ymaH
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.2|RNA chaperones]

    • [SW|Categories] containing this gene/protein

  • [SW|RNA chaperones]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,867,373 -> 1,867,594

    The protein

    Protein family

  • hfq family (according to Swiss-Prot)

    • Structure

  • [PDB|3HSB] (complex with an RNA aptamer) [Pubmed|22053080]

    • Expression and Regulation

    Operon

  • ''[protein|search|hfq]'' [Pubmed|23457461]

    • Regulation

  • repressed by glucose (7.7-fold) [Pubmed|12850135]
  • expression (mRNA levels) is quite constant during growth in minimal medium [Pubmed|23457461]
  • the Hfq protein amount increases upon transition to stationary phase [Pubmed|23457461]

    • Biological materials

    Mutant

  • GP22 (cat), available in the [SW|Jörg Stülke]'s lab

    • lacZ fusion

  • pGP460 (in [protein|search|pAC7]), available in [SW|Jörg Stülke]'s lab

    • two-hybrid system

  • B. pertussis adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in [SW|Jörg Stülke]'s lab

    • FLAG-tag construct

  • GP1067 (spc, based on [SW|pGP1331]), available in [SW|Jörg Stülke]'s lab

    • References

    Reviews

  • 17395525,15009882,21760622,26773797

    • Original publications

  • 12850135,20445260,23457461,22965117,22053080,24932523,25150227,25915524,27049793