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yonN
SP prophage-derived DNA-binding protein HU 2
function
untwisting of the DNA double helix
product
DNA-binding protein HU 2
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.8|Genetics/ other/ based on similarity][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]Gene
Coordinates
2,225,337 2,225,615
The protein
Catalyzed reaction/ biological activity
[protein|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|YonN]-mediated untwisting of the DNA stimulates [protein|C352560155F5B2E951B5059794D7B319C1A3AF2C|Nth] endonuclease activity at AP sites [Pubmed|21954439]Protein family
bacterial histone-like protein family (with [protein|EFD8FC875B6787B1512C5FC4C81E7E4C9BD93028|Hbs], according to UniProt)Paralogous protein(s)
[protein|EFD8FC875B6787B1512C5FC4C81E7E4C9BD93028|Hbs] Structure
[PDB|1HUE] ([protein|EFD8FC875B6787B1512C5FC4C81E7E4C9BD93028|Hbs] from B. stearothermophilus, 71% identity) [pubmed|7500343]Expression and Regulation
Operons
genes
[gene|121C3C9CF49711316A526B9571F020BE8E304B31|yonP]-[gene|34380A2F469ACFD90D450717A41D6F5CC19DCD7E|yonO]-[gene|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]
description
[pubmed|22383849]
Biological materials
Mutant
BKE21050 ([gene|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATCAATTTCCTCCTAA, downstream forward: _UP4_TAATCAGTTAATGAGGACGABKK21050 ([gene|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATCAATTTCCTCCTAA, downstream forward: _UP4_TAATCAGTTAATGAGGACGAReferences
