alkaline phosphatase III, heptaprenylglyceryl phosphate processing phosphatase
function
aquisition of phosphate upon phosphate starvation, ether lipid synthesis
product
alkaline phosphatase III, heptaprenylglyceryl phosphate processing phosphatase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|phosphate metabolism], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|PhoP regulon], [SW|SigE regulon]Gene
Coordinates on the chromosome (coding sequence)
620,097 -> 621,485
The protein
Catalyzed reaction/ biological activity
A phosphate monoester H2O = an alcohol phosphate (according to Swiss-Prot) Protein family
alkaline phosphatase family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|PhoA]Modification
phosphorylated on ser/ thr/ tyr [Pubmed|16493705]Structure
[PDB|3A52] (from ''Shewanella sp.'', 41% identity) [Pubmed|20057143][SW|Localization]
extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
Operon
''[protein|search|phoB]-[protein|search|ydhF]'' [Pubmed|10913081][SW|Sigma factor]
[protein|search|SigA], [protein|search|SigE] [Pubmed|15699190,16030210]Regulation
expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|9335276,10913081,16030210]Regulatory mechanism
[protein|search|PhoP]: transcription activation [Pubmed|9335276,10913081,16030210]Biological materials
Mutant
1A767 ( ''phoB''::''cat''), [Pubmed|9426145], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A767&Search=1A767 BGSC]References
16030210,9335276,8088554,10913081,16491025,8113174,9335276,18957862,16493705,25666134,20057143,27118079,27226549