SubtiBank SubtiBank
phrG [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

phrG [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

response regulator aspartate phosphatase (RapG) regulator
locus
BSU40310
pI
9.02
mw
4.00 kDa
function
control of DegU activity
product
phosphatase (RapG) regulator
essential
no
synonyms
yycL

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.3|Control of response regulators/ other]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
  • [category|SW 6|Groups of genes] → [category|SW 6.8|Short peptides]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription factors and their control], [SW|quorum sensing], [SW|short peptides]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|RghR regulon], [SW|SigH regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    4,141,358 -> 4,141,474

    The protein

    Catalyzed reaction/ biological activity

  • binds to [protein|search|RapG], this results in the inability of [protein|search|RapG] to interact with [protein|search|DegU] [Pubmed|12950930]
  • Protein family

  • phr family (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|PhrG]-[protein|search|RapG] [Pubmed|12950930]
  • Expression and Regulation

    Operon

  • ''[protein|search|rapG]-[protein|search|phrG]'' [Pubmed|12950930]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|16553878], SigH [Pubmed|12950930]
  • Regulation

  • repressed by [protein|search|SinR] [Pubmed|16430695]
  • repressed by [protein|search|RghR] [Pubmed|16553878]
  • repressed by glucose (4.8-fold) ([protein|search|CcpA]) [Pubmed|12850135]
  • Regulatory mechanism

  • [protein|search|SinR]: transcription repression [Pubmed|16430695]
  • [protein|search|RghR]: transcription repression [Pubmed|16553878]
  • [protein|search|CcpA]: transcription repression [Pubmed|12850135]
  • References

  • 16553878,12850135,12950930