You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ahpT

thiol disulfide oxidoreductase, reduces [protein|B283B702D917E310130BC33A40BF6A5853C3D4C1|AhpA]

locus

BSU_14230

6.33

17.66 kDa

protein length

148 aa Sequence Blast

gene length

447 bp Sequence Blast

function

protection of proteins against oxidative damage

product

thiol disulfide oxidoreductase

essential

synonyms

ykuV

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

Hide small RNAs Zoom:

categories

[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

Gene

Coordinates

1,492,875 1,493,321

The protein

[SW|Domains]

[SW|Thioredoxin domain] (aa 2-145) (according to UniProt)

Structure

[PDB|2B5X] (reduced form), [PDB|2B5Y] (oxidized form)

[SW|Localization]

cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

genes

[gene|B283B702D917E310130BC33A40BF6A5853C3D4C1|ahpA]-[gene|398E6FAC317D9BD81FB80A7CC9DF1CC757F2FA98|ahpT]

description

[Pubmed|20817675]

regulatory mechanism

view in new tab

Biological materials

Mutant

GP1729 [gene|search|ahpAT]::kan trpC2 available in [SW|Jörg Stülke]'s lab

MGNA-B344 (ykuV::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1343 NBRP B. subtilis, Japan]

BKE14230 ([gene|398E6FAC317D9BD81FB80A7CC9DF1CC757F2FA98|ahpT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGCTTTTTCCCTCCTAT, downstream forward: _UP4_TAGGTATCTGACTAAATAGT

BKK14230 ([gene|398E6FAC317D9BD81FB80A7CC9DF1CC757F2FA98|ahpT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGCTTTTTCCCTCCTAT, downstream forward: _UP4_TAGGTATCTGACTAAATAGT

References

20817675,16418167,26787766