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glyS [Mon Aug 31 2015 13:55:39 GMT+0200 (CEST)]
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glyS [Mon Aug 31 2015 13:55:39 GMT+0200 (CEST)]

glycyl-tRNA synthetase (beta subunit)
locus
BSU25260
pI
4.97
mw
76.00 kDa
function
translation
product
glycyl-tRNA synthetase (beta subunit)
essential
yes
ec
6.1.1.14
synonyms
yqfK
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.10|Aminoacyl-tRNA synthetases]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
    • syns
    yqfK

    [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|essential genes]

    • This gene is a member of the following [SW|regulons]

  • [SW|T-box]

    • Gene

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly) (according to Swiss-Prot)

    • Protein family

  • class-II aminoacyl-tRNA synthetase family (according to Swiss-Prot)

    • Structure

  • [PDB|1J5W] (from ''Thermotoga maritima'', 55% identity, 72% similarity)

    • [SW|Interactions]

  • [protein|search|GlyQ]-[protein|search|GlyS]

    • Expression and Regulation

    Operon

  • ''[protein|search|glyQ]-[protein|search|glyS]'' (according to [http://dbtbs.hgc.jp/COG/prom/glyQS.html DBTBS])

    • Regulation

  • induced by glycine limitation ([protein|search|T-box]) [Pubmed|19258532]

    • Regulatory mechanism

  • [protein|search|T-box]: [SW|RNA switch], transcriptional antitermination [Pubmed|19258532]

    • References

  • 15890195,15663928,19258532,15292140,16741230,26229106