SubtiBank SubtiBank
ydfM [2017-8-11 16:0:3]
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ydfM [2017-8-11 16:0:3]

primary manganese (II) efflux pump
locus
BSU05470
pI
6.16
mw
32.64 kDa
protein length
297 aa Sequence Blast
gene length
891 bp Sequence Blast
function
Mn(II) export
product
manganese (II) efflux pump
essential
no
synonyms
ydfM
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.13|Metal ion exporters]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.2|Trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)] → [category|SW 1.3.2.2|Manganese]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    595,109 → 596,002

    Phenotypes of a mutant

  • sensitive to Mn(II) [Pubmed|27748968]

    • The protein

    Catalyzed reaction/ biological activity

  • efflux of Mn(II) [Pubmed|27748968]

    • Protein family

  • cation diffusion facilitator (CDF) family [Pubmed|27748968]

    • Expression and Regulation

    Operons

    genes
    [gene|28C7CFE5701F6920652BE1973DC7A15D7C088E35|mneP]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|27748968], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|FF34DC303E8A7C9FAA205A6C2924961963B14EB1|MntR]: transcription activation, [Pubmed|27748968], in [regulon|FF34DC303E8A7C9FAA205A6C2924961963B14EB1|MntR regulon]

    • regulation

  • expressed at elevated Mn(II) concentrations ([protein|FF34DC303E8A7C9FAA205A6C2924961963B14EB1|MntR]) [Pubmed|27748968]
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    Biological materials

    Mutant

  • MGNA-C152 (ydfM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2150 NBRP B. subtilis, Japan]

    • References

  • 27748968