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sunT [Sun Dec 04 2016 12:34:57 GMT+0100 (CET)]
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sunT [Sun Dec 04 2016 12:34:57 GMT+0100 (CET)]

sublancin 168 lantibiotic ABC transporter
locus
BSU21470
pI
8.00
mw
81.00 kDa
function
sunA|sublancin export and processing
product
sublancin 168 lantibiotic ABC transporter
essential
no
synonyms
yolH
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.2|Export of antibiotic substances]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|miscellaneous metabolic pathways], [SW|biosynthesis of antibacterial compounds], [SW|SP-beta prophage], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|Abh regulon], [SW|AbrB regulon], [SW|Rok regulon], [SW|YvrHb regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    2,267,346 -> 2,269,463

    The protein

    [SW|Domains]

  • has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]

    • [SW|Localization]

  • membrane [Pubmed|10092453]

    • Expression and Regulation

    Operon

  • ''[protein|search|sunT]-[protein|search|bdbA]-[protein|search|sunS]-[protein|search|bdbB]'' [Pubmed|16306698]

    • Regulation

  • repressed by [protein|search|Rok] [Pubmed|15743949]

    • Regulatory mechanism

  • activated by [SW|YvrHb] [Pubmed|16306698]
  • [protein|search|Rok]: transcription repression [Pubmed|15743949]
  • [protein|search|AbrB]: transcription repression[Pubmed|20817675]
  • [protein|search|Abh]: transcription activation [Pubmed|20817675]

    • Additional information

  • the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]

    • References

    Reviews

  • 23106164

    • Original publications

  • 9722542,11872755,10092453,15743949,16306698,21815947,20817675