function
utilization of xylan and xylose
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.5|Utilization of xylan/ xylose][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|XylR regulon]The protein
Catalyzed reaction/ biological activity
D-xylose = D-xylulose (according to Swiss-Prot)Protein family
xylose isomerase family (according to Swiss-Prot)Structure
[PDB|1A0D] (Geobacillus stearothermophilus)[SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|xylA]-[protein|search|xylB]'' [Pubmed|1921970][SW|Sigma factor]
[protein|search|SigA] [Pubmed|2454911]Regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8132469]induction by xylose ([protein|search|XylR]) [Pubmed|2454911]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|8132469][protein|search|XylR]: transcription repression [Pubmed|2454911]Biological materials
Mutant
GP1151 (del aphA3) available in [SW|Stülke] lab1A719 (no resistance), [Pubmed|1719948], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A719&Search=1A719 BGSC]Labs working on this gene/protein
[SW|Wolfgang Hillen], Erlangen University, Germany [http://www.biologie.uni-erlangen.de/mibi/index2.html Homepage]References
7966270,1921970,8132469,2454911,1588910,22900538 
