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kbl [2017-8-11 16:0:3]
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kbl [2017-8-11 16:0:3]

2-amino-3-ketobutyrate CoA ligase
locus
BSU17000
pI
6.25
mw
43.12 kDa
protein length
392 aa Sequence Blast
gene length
1176 bp Sequence Blast
function
threonine utilization
product
2-amino-3-ketobutyrate CoA ligase
essential
no
ec
2.3.1.29
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.8|Utilization of threonine/ glycine]
  • Gene

    Coordinates
    1,771,517 → 1,772,695

    The protein

    Catalyzed reaction/ biological activity

  • Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate (according to Swiss-Prot)
  • Protein family

  • class-II pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Modification

  • pyridoxal-phosphate (according to Swiss-Prot)
  • Structure

  • [PDB|1FC4] (from ''Escherichia coli'', 40% identity, 60% similarity) [Pubmed|11318637]
  • Expression and Regulation

    Operons

    genes
    [gene|8E64B62F15B92A2AACD68B913909100AE276D114|tdh]-[gene|1BC05699DEB3A16944FB8305F22976AED75805E8|kbl]
    description
    [Pubmed|22383849]
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    References

  • 11318637,22960854