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ydfJ
similar to antibiotic transport-associated protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
589,717 591,891
The protein
Protein family
resistance-nodulation-cell division (RND) (TC 2.A.6) family (with [protein|1632474628BEA113F297897D152276A1AB73BAE8|YdgH] and [protein|AAC32230E3E585932A876737131C3E2C15168B2A|SwrC], according to UniProt)Structure
[PDB|6N3T] (from Mycobacterium smegmatis, 25% identity) [pubmed|31113875][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|1B61298ECA583D2112AA56A88358E8A9A55D2C9D|ydfJ]
description
[pubmed|22383849]
regulatory mechanism
[protein|EFEAF09E4449A022A7323450FDED9458426A0080|YdfI]: activation, [Pubmed|15941986], in [regulon|EFEAF09E4449A022A7323450FDED9458426A0080|YdfI regulon]view in new tabBiological materials
Mutant
MGNA-C149 (ydfJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2147 NBRP B. subtilis, Japan]BKE05430 ([gene|1B61298ECA583D2112AA56A88358E8A9A55D2C9D|ydfJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATAATCTCCTTTCAAC, downstream forward: _UP4_TAATAGAAAAAGCAGATCTTBKK05430 ([gene|1B61298ECA583D2112AA56A88358E8A9A55D2C9D|ydfJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATAATCTCCTTTCAAC, downstream forward: _UP4_TAATAGAAAAAGCAGATCTTReferences