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cmk [2019-08-07 08:45:12]

cytidylate kinase (CMP, dCMP)

locus

BSU_22890

5.00

24.95 kDa

protein length

224 aa Sequence Blast

gene length

675 bp Sequence Blast

function

synthesis of CTP and dCTP

product

cytidylate kinase (CMP, dCMP)

essential

yes

2.7.4.14

synonyms

jofC,ypfC

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.4|Biosynthesis/ acquisition of pyrimidine nucleotides]

[category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates

2,396,045 2,396,719

Phenotypes of a mutant

essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

ATP + CMP --> ADP + CDP (according to UniProt)

Protein family

cytidylate kinase family (single member, according to UniProt)

Structure

[PDB|1CKE] (from ''Escherichia coli'', 38% identity, 54% similarity) [Pubmed|9862805]

Expression and Regulation

Operons

genes

[gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|ypfD]

description

[pubmed|22383849]

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genes

description

[pubmed|22383849]

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genes

description

[pubmed|22383849]

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genes

description

[pubmed|22383849]

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References

9126287