SubtiBank SubtiBank
spoIIM [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]
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spoIIM [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

required for dissolution of the septal cell wall
locus
BSU23530
pI
9.00
mw
24.00 kDa
function
dissolution of the septal cell wall
product
sporulation protein
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall/ other], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigE regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,450,403 -> 2,451,047

    The protein

    [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • the complex of [SW|SpoIID], [SW|SpoIIM], and [SW|SpoIIP] localizes at the leading edge of the mother cell engulfing membrane and is essential and rate limiting for membrane migration [Pubmed|20382772,12502745]
  • [SW|Interactions]

  • [SW|SpoIIP]-[SW|SpoIIM] [Pubmed|17376078]
  • Expression and Regulation

    Operon

  • ''spoIIM'' [Pubmed|8501065]
  • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|8501065]
  • Regulation

  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|8501065]
  • subject to negative control by [protein|search|YlbO] [Pubmed|15383836]
  • References

  • 17376078,11886548,15752199,8501065,15383836,23859254,20382772,12502745